Instead of following God’s leading, Isaac followed his appetite. “Whose God is their belly.” Phil. 3:19
Rom. 8:6-8 “For the mind set on the flesh is death, but the mind set on the Spirit is life and peace, 7 because the mind set on the flesh is hostile toward God; for it does not subject itself to the law of God, for it is not even able to do so, 8 and those who are in the flesh cannot please God.”
Like Isaac, Esau was more interested in food than in the promise of God.